Platelet-Rich Plasma (PRP) Post-Procedure Instructions

Posted on 
October 1, 2025

Platelet Rich Plasma (PRP) treatments use concentrated growth factors from your blood that are injected into the area of injury. You will not feel pain relief from the procedure right away, and you will likely experience an increase in discomfort after the procedure. Tendon injections often have a significant increase in pain post procedure that can last several days. Joints can take 6 weeks to start feeling better and tendons can take 8 weeks to start feeling better. Maximum improvement takes place over a period of several months.

Orthobiologic treatments have not been authorized by the FDA and are considered experimental by the FDA.

Discontinue any Anti-Inflammatory anti-platelet medications:

  • Advil
  • Aleve
  • Aspirin
  • Celebrex
  • Coumadin
  • Diclofenac
  • Fish Oil
  • Ibuprofen
  • Meloxicam
  • Nabumetone
  • Naproxen
  • Plavix
  • Xarelto
  • Do not discontinue antiplatelet therapy without discussing with your primary physician first.

What do I need to prepare for injections:

  • Bring a driver
  • Bring DME (durable medical equipment) such as: crutches, boots, sling, splint, etc.
  • Drink lots of water for 48 hours prior to your injection

Compression:

  • If the PRP is in your hip, groin or thigh please bring compression shorts with you.
  • We will provide a compression sleeve for all other areas.

Activity:

  • Do not submerge the injection site for the first 48 hours following injection. You may shower but no baths or hot tubs where the site would be completely submerged by water.
  • Please discuss possible work/activity restrictions prior to the procedure.
  • Rest the area for the first 2-3 days.
  • No excessive activity for the first 2 weeks.
  • Return to activities will be determined by your medical team on the day of the procedure.
  • Physical therapy will begin after 1-2 weeks.

Pain Control:

It is common to have pain and swelling after the procedure. Pain often lasts 3-4 days but may last up to 2 weeks after the injection.

Ice:

  • You may use ice for pain control 1-2 days after the procedure for 15-20 minutes at a time. Allow at least 30 minutes before repeating.
  • Do not use ice after the second day.
  • Do not apply heat the first 3-4 days after the injection.

Medications:

  • You may use acetaminophen (Tylenol) over the counter if needed.
  • Avoid non-steroidal anti-inflammatories (NSAIDs) for at least 2 weeks after and up to 6 weeks after the procedure if able.

Please call us if any of the following happen:

  • Fever over 101 degrees F (or 39.0 C)
  • Redness or drainage at the injection site
  • New weakness, numbness or tingling at or below the level of the injections
  • Any other concerns

We are tracking patient clinical outcomes. What does that mean?

We use a secure data tracking system called Data Biologics. You'll receive an email to complete a survey the day of the treatment and a few months post treatment. This data allows us to compare our patient outcomes to other providers across the country to help us better modify our protocols and individualized treatment plans.

Forté Sports Medicine and Orthopedics provides exceptional care tailored to our patients’ needs. With over 40 years of experience, our team of providers and clinicians know the importance of putting patients first. Our flexibility and comprehensive services mean you can see a physician, get diagnostic imaging, and start treatment all in one convenient location. Contact us today to request an appointment.  We’ll help you take the next step toward a pain-free life.

If you have questions on pricing, please click here.

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Our Tipton office will be closed Friday, October 10th.

 

Starting Monday, October 5th -Travel routes to our Carmel Forté office have been impacted by road closures for the Level Up 31 project. Please add extra travel time for your appointments.

• Closure of the southbound U.S. 31 ramp to 106th Street through late-December
• Closure of eastbound 106th Street at U.S. 31 through late-December
• Closure on the eastbound I-465 ramp to southbound Meridian Street through mid-December

Visit https://levelup31.com/ for more details

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